Giulia Caron
Associate Professor
- Department of Molecular Biotechnology and Health Sciences
- SSD: CHIM/08 - pharmaceutical chemistry
- ORCID: orcid.org/0000-0002-2417-5900
Contacts
- 0116708337
- Call Giulia Caron
- giulia.caron@unito.it
- Dipartimento di Biotecnologie Molecolari e Scienze per la Salute
Centro dell'Innovazione
via Quarello 15
10125 Torino - https://www.dmbhs.unito.it/persone/giulia.caron
- Contacts VCard
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- Department of Molecular Biotechnology and Health Sciences
- Dipartimento di Biotecnologie Molecolari e Scienze per la Salute
- Biotechnological and Chemical Sciences in Diagnostics
- Corso di Laurea in Biotecnologie
- Corso di laurea magistrale in Chimica Clinica Forense e dello Sport
- Master Program in Molecular Biotechnology
- Dottorato in Scienze Farmaceutiche e Biomolecolari
Curriculum vitae
Curriculum Vitae
(0.2 MB) Selected research products
- G. Ermondi, M. Vallaro, G. Caron (2018), Learning how to use IAM chromatography for predicting permeability. Eur. J. Pharm. Sci, vol. 14, pp. 385-390.
- G. Caron, M. Vallaro, G. Ermondi (2017), The need of implementing Intramolecular Hydrogen Bonding (IMHB) considerations in drug discovery. Measuring the propensity of compounds to form IMHBs. Med. Chem. Comm, vol. 8, pp.1143-1151.
- G. Caron and G. Ermondi (2017), Why we need to implement intramolecular hydrogen bonding considerations in drug discovery. Fut. Med. Chem. vol. 9, pp. 1-5.
- G. Caron and G. Ermondi (2017), Updating molecular properties in early drug discovery. DDT, vol 22, pp. 835-840
- G. Goetz, M. Shalaeva, G. Caron, G. Ermondi, L. Philippe (2017), Relating passive permeability to molecular polarity using Block Relevance analysis. Mol. Pharmaceut. vol. 14, pp. 386-393.
- G. Caron and G. Ermondi (2016), Molecular descriptors for polarity: the need of going beyond PSA. Fut. Med. Chem. vol. 8, pp 2013-2016.
- G. Ermondi, G.Caron (2016), Do surface-based match solution-based techniques? The case of drug-liposome interaction, Int. J. Pharm. vol. 508(1-2), pp. 123-127. doi: 10.1016/j.ijpharm.2016.05.018
- G. Caron, M. Vallaro, G. Ermondi, G. H. Goetz, Y. A. Abramov, L. Philippe, M. Shalaeva (2016), A Fast Chromatographic Method for Estimating Lipophilicity and Ionization in Nonpolar Membrane-Like Environment, Mol. Pharmaceut. vol.13 (3), pp. 1100-1110.
- G. Ermondi, F. Catalano, M. Vallaro, I. Ermondi, M.P. Camacho Leal, L. Rinaldi, S. Visentin, G. Caron (2015), Lipophilicity of amyloid ß-peptide 12-28 and 25-35 to unravel their ability to promote hydrophobic and electrostatic interactions, Int. J. Pharm. vol 495(1), pp. 179-85.
- 10. G. Caron, S. Visentin, C. Pontremoli, G. Ermondi (2015), Profile of the intermolecular forces governing the interaction of drugs with mucin, Int. J. Pharm. vol. 488, pp. 67-69.
Courses
- ADVANCED DRUG DISCOVERY (BIO0161 Pds 308-BIDD)
Master Program in Molecular Biotechnology - Basic methods in drug discovery (Sezione 1) (BIO0174A)
Corso di Laurea in Biotecnologie - COMPUTATIONAL DRUG DISCOVERY (BIO0220)
Biotechnological and Chemical Sciences in Diagnostics - COMPUTATIONAL DRUG DISCOVERY (BIO0220)
Corso di Laurea in Biotecnologie - COMPUTATIONAL DRUG DISCOVERY (BIO0220 Pds GEN)
Master Program in Molecular Biotechnology - Chemistry for Health Sciences
Dottorato in Scienze Farmaceutiche e Biomolecolari - Chimica Farmaceutica (Sostanze Dopanti e dAbuso) (CHI0074)
Corso di laurea magistrale in Chimica Clinica Forense e dello Sport - Drug Discovery: concepts and techniques
Dottorato in Scienze Farmaceutiche e Biomolecolari - INTEGRATED LABORATORY TECNIQUES (BIO0174)
Corso di Laurea in Biotecnologie
Research topics
Gruppi di ricerca
Drug discovery: descrittori di ionizzazione. lipofilia, polarità e permeabilità specifici per composti beyond-rule-of-5 (bRo5)
La ricerca della prof. Caron si inserisce nel contesto del drug discovery e si focalizza principalmente nel progettare ed implementare descrittori chimico-fisici sperimentali e computazionali (es. descrittori di ionizzazione, lipopfilia, permeabilità) specifici per la caratterizzazione di composti con struttura grande e flessibile (anche chiamati i composti che stanno al di là della regola del 5 di Lipinski).
Maggiori informazioni possono essere reperite nelle pubblicazioni.
Drug discovery: Ionization, lipophilicity, polarity and permeability descriptors for beyond-rule-of-5 (bRo5) compounds
Prof. Caron reserch interests concern drug discovery and mostly focus on designing and implementing experimental and computational physico-chemical descriptors (e.g. ionization, lipophilicity, permeability, etc) specific for large and flexible compounds (also called beyond-Rule-of-5 compounds).
More details can be found in published papers
Activities in agenda
Academic bodies
Office hours
In principle from Monday to Friday from 9 to 12.Skype calls are encouraged