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Sonja Visentin

In our group we apply medicinal chemistry based approaches and nanotechnology-based systems to improve drug targeting and delivery.
Main topics:

  • gold nanoparticles for radiotherapy and hadrontherapy. Both approaches rely on the damage caused to cells by ionizing radiation, which is released mostly on cancer cells by means of IMRT techniques (Radiotherapy) or energy tuning (Hadrontherapy)  (INFN financed project).
  • Carbon nanotubes and Halloysite nanotubes(PRIN 2010-2011)used as drug delivery systems.
  • ZnO nanostructures for photodynamic and sonodynamic therapy.
  • Nanostructured-initiators for matrix-free, surface-based mass spectrometry imaging of antitumor drugs in tissues (Cariplo grant)Mass spectrometry imaging (MSI) is one of the latest, rapidly growing, innovative techniques in mass spectrometry (MS). It is used to visualize molecular distribution in a two-dimensional space of a sample attached to an electric conductive steel plate or glass slide. In this context, the goal of this study is the development of specifically designed surfaces for the imaging of antitumor drugs, after administration, in normal organs or tumors tissue of mice, with high spatial resolution and sensitivity.

For more infos please refer to www.casmedchem.unito.it  

 

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