Department of Molecular Biotechnology and Health Sciences

Publications

Courses

• BASIC AND APPLIED MOLECULAR BIOLOGY (BIO0226)
  Biotechnological and Chemical Sciences in Diagnostics
• BIOLOGIA MOLECOLARE E BIOINFORMATICA (BIO0223)
  Corso di Laurea in Biotecnologie
• Basi biologiche, molecolari e di genetica umana (canale B) (SME0881)
  Laurea Magistrale in Medicina e Chirurgia - sede di Torino
• Biologia Molecolare (BIO0223A)
  Corso di Laurea in Biotecnologie
• Biologia molecolare (canale B) (SME0881B)
  Laurea Magistrale in Medicina e Chirurgia - sede di Torino
• GENOMICS AND EPIGENOMICS (BIO0143 Pds 306-TB)
  Master Program in Molecular Biotechnology
• Genomics and Epigenomics of Gene Regulation (BIO0143B Pds 306-TB)
  Master Program in Molecular Biotechnology
• Ruoli non convenzionali del fattore di trascrizione pro-oncogenico Stat3 nel regolare il metabolismo energetico delle cellule tumorali. Responsabile prof Valeria Poli
  Programma MD-PhD della Scuola di Medicina
• SCIENTIFIC COMMUNICATION (BIO0120 Pds GEN)
  Master Program in Molecular Biotechnology
• Scientific communication (2) (BIO0120B Pds GEN)
  Master Program in Molecular Biotechnology
• Seminario della Scuola di Dottorato in Medicina Molecolare, Prof. Flavia Bazzoni, 15 marzo 2010
  Dottorato in Medicina Molecolare
• TIROCINIO di BIOLOGIA MOLECOLARE PER LO STUDIO DI AUTOIMMUNITA' E TUMORIGENESI (SME0571)
  Corso di Laurea Magistrale in Biotecnologie Mediche - Classe LM-9

Research topics

Throughout her career, Valeria Poli was interested in studying inflammatory cytokines signaling pathways and the pathological consequences of their dysregulation. In recent years the laboratory has focused particularly on the analysis of the biological functions of the transcription factor STAT3. These studies allowed us to demonstrate how aberrant STAT3 constitutive activities may drive oncogenesis (Barbieri et al., Cancer Res 2010), and helped to unveil a new role of constitutively activated STAT3 in regulating cell energy metabolism (Demaria et al., Ageing 2010; Cell Death and Differentiation 2012). Recently we have opened a new line of research aimed at clarifying STAT3 functions in heart auto-immunity and cardiac inflammation (Camporeale, Marino et al., EMBO Mol Med 2013). The main present projects in the laboratory include characterization of  the canonical and non-canonical functions of STAT3 and its target RNAs in mammary tumorigenesis, unveiling the role of the mesenchymal stroma (Cancer Associated Fibroblasts) in supporting tumor growth and metastasis in breast and prostate cancer, identification and functional validation of non coding RNAs regulated by STAT3 in health and disease conditions, and the identification of targeted therapeutic approaches to cure auto-immune myocarditis.

Gruppi di ricerca

• Gene expression control in tumor biology

• Role of the axis IL-6/STAT3/complement in regulating chronic inflammation and heart auto-immunity

Activities in agenda

See my calendar

Academic bodies

• Research Commission

• Consiglio di Dipartimento

• Erasmus Committee

• Collegio Docenti

Office hours