Department of Molecular Biotechnology and Health Sciences

Selected research products

Relevant publications

1. Clemente N, Baroni S, Fiorilla S, Tasso F, Reano S, Borsotti C, Ruggiero MR, Alchera E, Corrazzari M, Walker G, Follenzi A, Geninatti Crich S, Carini R (2023) Boosting intracellular sodium selectively kills hepatocarcinoma cells and induces hepatocellular carcinoma tumor shrinkage in mice. Commun Biol 6, 574. https://doi.org/10.1038/s42003-023-04946-4
2. Ruggiero MR, Ait Itto H, Baroni S, Pierre S, Boutonnat J, Broche LM, Aime S, Berger F, Geninatti Crich S, Lahrech H. Role of Transmembrane Water Exchange in Glioma Invasion/Migration: In Vivo Preclinical Study by Relaxometry at Very Low Magnetic Field. Cancers. 2022; 14(17):4180. https://doi.org/10.3390/cancers14174180
3. Ruggiero MR, Baroni S, Bitonto V, Ruiu R, Rapisarda S, Aime S, Geninatti Crich S (2021) Intracellular Water Lifetime as a Tumor Biomarker to Monitor Doxorubicin Treatment via FFC-Relaxometry in a Breast Cancer Model. Frontiers in Oncology 11, 5191, DOI: 10.3389/fonc.2021.778823

Research topics

Current research activities: development of new diagnostic applications based on the study of relaxation processes and molecular dynamics in biological tissues, in vitro and in vivo; development of scaffolds for regenerative medicine applications.

Gadolinium based MRI contrast agents

MRI at low magnetic field and Boron Neutron Capture Therapy Agents

Research groups

• Imaging Molecolare