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Department of Molecular Biotechnology and Health Sciences

Department of Molecular Biotechnology and Health Sciences

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Paolo Ettore Porporato

Associate Professor

Contacts

At

  • Department of Molecular Biotechnology and Health Sciences
  • Dipartimento di Biotecnologie Molecolari e Scienze per la Salute
  • Corso di Laurea in Biotecnologie
  • Laurea Magistrale in Medicina e Chirurgia - sede di Torino
  • Master Program in Molecular Biotechnology
  • Scuola Universitaria Interdipartimentale in Scienze Strategiche (SUISS)
  • Ph.D. Program in Biomedical Sciences and Oncology

Curriculum vitae

  • Curriculum Vitae (0.2 MB)

    • Research products

    All my research products

    Selected research products

    Wyart, Elisabeth, Reano, Simone, Hsu, Myriam Y, Longo, Dario Livio, Li, Mingchuan, Hirsch, Emilio, Filigheddu, Nicoletta, Ghigo, Alessandra, Riganti, Chiara, Porporato, Paolo Ettore (2018)
    Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting.
    https://iris.unito.it/handle/2318/1670017

    Porporato, Paolo Ettore, Filigheddu, Nicoletta, Pedro, José Manuel Bravo-San, Kroemer, Guido, Galluzzi, Lorenzo (2018)
    Mitochondrial metabolism and cancer.
    https://iris.unito.it/handle/2318/1661659

    De Santis, Maria Chiara, Porporato, Paolo Ettore, Martini, Miriam*, Morandi, Andrea (2018)
    Signaling pathways regulating redox balance in cancer metabolism.
    https://iris.unito.it/handle/2318/1691013

    Li, Mingchuan, Sala, Valentina, De Santis, Maria Chiara, Cimino, James, Cappello, Paola, Pianca, Nicola, Di Bona, Anna, Margaria, Jean Piero, Martini, Miriam, Lazzarini, Edoardo, Pirozzi, Flora, Rossi, Luca, Franco, Irene, Bornbaum, Julia, Heger, Jacqueline, Rohrbach, Susanne, Perino, Alessia, Tocchetti, Carlo G, Lima, Braulio H F, Teixeira, Mauro M, Porporato, Paolo E, Schulz, Rainer, Angelini, Annalisa, Sandri, Marco, Ameri, Pietro, Sciarretta, Sebastiano, Lima-Júnior, Roberto César P, Mongillo, Marco, Zaglia, Tania, Morello, Fulvio, Novelli, Francesco, Hirsch, Emilio, Ghigo, Alessandra (2018)
    Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth.
    https://iris.unito.it/handle/2318/1662394

    Bindels, Laure B , Porporato, Paolo E , Ducastel, Sarah, Sboarina, Martina, Neyrinck, Audrey M , Dewulf, Evelyne M , Feron, Olivier, Lestavel, Sophie, Cani, Patrice D , Staels, Bart, Sonveaux, Pierre, Delzenne, Nathalie M (2017)
    Ffar2 expression regulates leukaemic cell growth in vivo.
    https://iris.unito.it/handle/2318/1661703

    Danhier, Pierre, Bański, Piotr, Payen, Valéry L, Grasso, Debora, Ippolito, Luigi, Sonveaux, Pierre, Porporato, Paolo E (2017)
    Cancer metabolism in space and time: Beyond the Warburg effect.
    https://iris.unito.it/handle/2318/1638236

    Baldini N, De Milito A, Feron O, Gillies RJ, Michiels C, Otto AM, Pastoreková S, Pedersen SF, Porporato PE, Sonveaux P, Supuran CT, Avnet S (2017)
    Annual meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic networks in cancer.
    https://iris.unito.it/handle/2318/1678772

    Payen, Valéry L , Hsu, Myriam Y , Rädecke, Kristin S , Wyart, Elisabeth, Vazeille, Thibaut, Bouzin, Caroline, Porporato, Paolo E , Sonveaux, Pierre* (2017)
    Monocarboxylate transporter MCT1 promotes tumor metastasis independently of its activity as a lactate transporter.
    https://iris.unito.it/handle/2318/1661661

    Contino S, Porporato PE, Bird M, Marinangeli C, Opsomer R, Sonveaux P, Bontemps F, Dewachter I, Octave JN, Bertrand L, Stanga S, Kienlen-Campard P (2017)
    Presenilin 2-dependent maintenance of mitochondrial oxidative capacity and morphology.
    https://iris.unito.it/handle/2318/1678774

    Pérez-Escuredo, Jhudit, Dadhich, Rajesh K, Dhup, Suveera, Cacace, Andrea, Van Hée, Vincent F, De Saedeleer, Christophe J, Sboarina, Martina, Rodriguez, Fabien, Fontenille, Marie-Joséphine, Brisson, Lucie, Porporato, Paolo E, Sonveaux, Pierre (2016)
    Lactate promotes glutamine uptake and metabolism in oxidative cancer cells.
    https://iris.unito.it/handle/2318/1657310

    Porporato, P E (2016)
    Understanding cachexia as a cancer metabolism syndrome.
    https://iris.unito.it/handle/2318/1657312

    Avnet, S, Baldini, N, Di Pompo, G, Sonveaux, P, Zini, N, Porporato, Pe, Sboarina, M, Lemma, S (2016)
    Energy metabolism in osteoclast formation and activity.
    https://iris.unito.it/handle/2318/1657307

    Porporato, Paolo E , Payen, Valéry L , Pérez-Escuredo, Jhudit, De Saedeleer, Christophe J , Danhier, Pierre, Copetti, Tamara, Dhup, Suveera, Tardy, Morgane, Vazeille, Thibaut, Bouzin, Caroline, Feron, Olivier, Michiels, Carine, Gallez, Bernard, Sonveaux, Pierre (2014)
    A mitochondrial switch promotes tumor metastasis.
    https://iris.unito.it/handle/2318/1657315

    De Saedeleer, C J , Porporato, P E , Copetti, T , Pérez-Escuredo, J , Payen, V L , Brisson, L , Feron, O , Sonveaux, P (2014)
    Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration.
    https://iris.unito.it/handle/2318/1657316

    Steinstraesser, Lars, Lam, Martin C, Jacobsen, Frank, Porporato, Paolo E, Chereddy, Kiran Kumar, Becerikli, Mustafa, Stricker, Ingo, Hancock, Robert EW, Lehnhardt, Marcus, Sonveaux, Pierre, Préat, Véronique*, Vandermeulen, Gaëlle (2014)
    Skin electroporation of a plasmid encoding hCAP-18/LL-37 host defense peptide promotes wound healing.
    https://iris.unito.it/handle/2318/1681346

    Porporato P, Filigheddu N, Reano S, Ferrara M, Angelino E, Gnocchi V, Prodam F, Ronchi G, Fagoonee S, Fornaro M, Chianale F, Baldanzi G, Surico N, Sinigaglia F, Perroteau I, Smith R, Sun Y, Geuna S, Graziani A (2013)
    Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice.
    https://iris.unito.it/handle/2318/132179

    Porporato, Paolo E , Payen, Valéry L , De Saedeleer, Christophe J , Prã©at, Vã©ronique, Thissen, Jean-Paul, Feron, Olivier, Sonveaux, Pierre (2012)
    Lactate stimulates angiogenesis and accelerates the healing of superficial and ischemic wounds in mice.
    https://iris.unito.it/handle/2318/1658090

    Federica Chianale, Elena Rainero, Cristina Cianflonea, Valentina Bettio, Andrea Pighini, Paolo Porporato, Nicoletta Filigheddu, Guido Serini, Fabiola Sinigaglia, Gianluca Baldanzi, Andrea Graziani (2010)
    Diacylglycerol kinase α mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI.
    https://iris.unito.it/handle/2318/76313

    Audisio C, Raimondo S, Nicolino S, Gambarotta G, Di Scipio F, Macrì L, Montarolo F, Giacobini-Robecchi MG, Porporato P, Filigheddu N, Graziani A, Geuna S, Perroteau I (2009)
    Morphological and biomolecular characterization of the neonatal olfactory bulb ensheathing cell line.
    https://iris.unito.it/handle/2318/131011

    Geuna S, Raimondo S, Ronchi G, Audisio C, Perroteau I, Porporato P, Filigheddu N, Graziani A (2009)
    Increase in circulating des-acyl ghrelin promotes posttraumatic neural regeneration in the mouse peripheral nervous system.
    https://iris.unito.it/handle/2318/70642

    Rainero E , Chianale F , Porporato P , Cianflone C , Bettio V , Filigheddu N , Serini G , Graziani A (2009)
    HGF induces cell migration, ruffling and Rac activation through a novel signalling pathway coupling diacylglycerol kinase alpha to PKCz/i and RhoGDI.
    https://iris.unito.it/handle/2318/95638

    BALDANZI G, CUTRUPI S, CHIANALE F, GNOCCHI V, RAINERO E, PORPORATO P, FILIGHEDDU N, VAN BLITTERSWIJK WJ, PAROLINI O, BUSSOLINO F, SINIGAGLIA F, GRAZIANI A (2008)
    Diacylglycerol kinase-alpha phosphorylation by Src on Y335 is required for activation, membrane recruitment and Hgf-induced cell motility.
    https://iris.unito.it/handle/2318/35817

    FILIGHEDDU N, CUTRUPI S, PORPORATO PE, RIBONI F, BALDANZI G, CHIANALE F, FORTINA E, PIANTANIDA P, M DE BORTOLI, VACCA G, GRAZIANI A, SURICO N (2007)
    Diacylglycerol Kinase is Required for HGF-induced Invasiveness and Anchorage-independent Growth of MDA-MB-231 Breast Cancer Cells.
    https://iris.unito.it/handle/2318/4341

    CHIANALE F, S CUTRUPI, RAINERO E, BALDANZI G, PORPORATO PE, TRAINI S, FILIGHEDDU N, GNOCCHI VF, SANTORO MM, PAROLINI O, VAN BLITTERSWIJK WJ, SINIGAGLIA, F, GRAZIANI A (2007)
    Diacylglycerol Kinase-{alpha} Mediates HGF-induced Epithelial Cell Scatter by Regulating Rac Activation and Membrane Ruffling.
    https://iris.unito.it/handle/2318/21544

    FILIGHEDDU N, GNOCCHI VF, COSCIA M, CAPPELLI M, PORPORATO PE, TAULLI R, TRAINI S, BALDANZI G, CHIANALE F, CUTRUPI S, ARNOLETTI E, GHE C, FUBINI A, SURICO N, SINIGAGLIA F, PONZETTO C, MUCCIOLI G, CREPALDI T, GRAZIANI A (2007)
    Ghrelin and Des-Acyl Ghrelin Promote Differentiation and Fusion of C2c12 Skeletal Muscle Cells.
    https://iris.unito.it/handle/2318/39617

    A GRAZIANI, V GNOCCHI, N FILIGHEDDU, M COSCIA, L BADA, F SOTTINI, S TRAINI, P PORPORATO, F CHIANALE, G BRIGNOLI, G BALDANZI, R TAULLI, T CREPALDI, F SINIGAGLIA (2006)
    Ghrelin induces differentiation and fusion of C2C12 myoblasts and protects myotubes from atrophy.
    https://iris.unito.it/handle/2318/70015

    Bondi A, Valentino P, Daraio F, Porporato P, Gramaglia E, Carturan S, Gottardi E, Camaschella C, Roetto A (2005)
    Hepatic expression of hemochromatosis genes in two mouse strains after phlebotomy and iron overload.
    https://iris.unito.it/handle/2318/147939

    Roetto A, Daraio F, Porporato P, Caruso R, Cox TM, Cazzola M, Gasparini P, Piperno A, Camaschella C (2004)
    Screening hepcidin for mutations in juvenile hemochromatosis: identification of a new mutation (C70R).
    https://iris.unito.it/handle/2318/147857

    C Camaschella, S Bosio, M De Gobbi, G Zecchina, F Daraio, P Porporato, F Longo, A Piga, A Roetto (2003)
    Rare Genetic Anemias Due to Defective Iron Recycling: Aceruloplasminemia and Type 4 Hemochromatosis.
    https://iris.unito.it/handle/2318/123109

    A Roetto, F Daraio, F Alberti, P Porporato, A Calì, M De Gobbi, C Camaschella (2002)
    Hemochromatosis due to mutations in transferrin receptor 2.
    https://iris.unito.it/handle/2318/90159

    Courses

    Research topics

    Gruppi di ricerca

    Cancer Metabolism And Cachexia

     

     

    Academic bodies

    Last update: 27/01/2022 12:42
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